Acenocoumarol supplier & exporter
Product Description
API name | Acenocoumarol |
CAS Number | 152-72-7 |
Therapeutic Category | Anticoagulant |
Route of Administration | Tablet |
Regulatory Documents | TECH PACK, DMF |
Trader & Wholesaler of Acenocoumarol
Mechanism of Action:
Acenocoumarol inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent clotting factors, this limitsanticoagulant proteins C and S is inhibited resulting in decreased prothrombin levels and a decrease in the amount of thrombin generated and bound to fibrin. This reduces the thrombogenicity of clots.the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulant proteins.
Drug Indications:
Acenocoumarol is an anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.