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Alendronate Sodium

Alendronate Sodium supplier & exporter

Product Description

API name Alendronate Sodium
CAS Number 121268-17-5
Therapeutic Category Antiosteoporotic
Route of Administration Tablet
Regulatory Documents USDMF, CEP, ASMF, CANADA DMF, TAIWAN DMF, DMF, JDMF, CEP, WC

 

Trader & Wholesaler of Alendronate Sodium

Mechanism of Action:


Alendronic acid binds to bone hydroxyapatite. Bone resorption causes local acidification, releasing alendronic acid which is that taken into osteoclasts by fluid-phase endocytosis. Endocytic vesicles are acidified, releasing alendronic acid to the cytosol of osteoclasts where they induce apoptosis.

Drug Indications:

Alendronic acid is indicated for the treatment and prevention of osteoporosis in men and postmenopausal women, treatment of glucocorticoid-induced osteoporosis, and Paget’s disease of bone.

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