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Adrenaline Acid Tartrate supplier & exporter

Product Description

Trader & Wholesaler of Adrenaline Acid Tartrate

Mechanism of Action:

Adrenaline has a strong vasoconstrictor action through alpha- adrenergic stimulation. This activity counteracts the vasodilatation and increased vascular permeability leading to loss of intravascular fluid and subsequent hypotension, which are the major pharmacological features in anaphylactic shock.

Drug Indications:

Adrenaline may be used to provide rapid relief of severe hypersensitivity reaction to drugs and other allergens, and in the emergency treatment of anaphylactic shock.

Adenosylcobalamin supplier & exporter

Product Description

Trader & Wholesaler of Adenosylcobalamin

Mechanism of Action:

A number of vicinal diols were found to react with propanediol dehydratase, typically resulting in the conversion of enzyme-bound adenosylcobalamin to cob(II)alamin and formation of aldehyde or ketone derives from substrate. Moreover, all are capable of effecting the irreversible inactivation of the enzyme.

Drug Indications:

Adenosylcobalamin is an active form of vitamin B12, a water-soluble vitamin used as a nutritional supplement to treat vitamin B12 deficiency or pernicious anemia, stomatitis, as well as for other conditions like depression, panic attacks and anxiety.

Adenosine supplier & exporter

Product Description

Trader & Wholesaler of Adenosine

Mechanism of Action:

Agonism of adenosine receptors A1 and A2 reduces conduction time in the atrioventricular node of the heart.4,6,12 Conduction time is decreased by inducing potassium efflux and inhibiting calcium influx through channels in nerve cells, leading to hyperpolarization and and increased threshold for calcium dependent action potentials.4 Decreased conduction time leads to an antiarrhythmic effect.4 Inhibition of calcium influx, reduces the activity of adenylate cyclase, relaxing vascular smooth muscle.6 Relaxed vascular smooth muscle leads to increased blood flow through normal coronary arteries

Drug Indications:

Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy in patients unable to adequately exercise.12 It is also indicated to convert sinus rhythm of paroxysmal supraventricular tachycardia.

Adefovir Dipivoxil supplier & exporter

Product Description

Trader & Wholesaler of Adefovir Dipivoxil

Mechanism of Action:

Adefovir dipivoxil is a prodrug of adefovir. Adefovir is an acyclic nucleotide analog of adenosine monophosphate which is phosphorylated to the active metabolite adefovir diphosphate by cellular kinases. Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) by competing with the natural substrate deoxyadenosine triphosphate and by causing DNA chain termination after its incorporation into viral DNA.

Drug Indications:

Indicated for the treatment of chronic hepatitis B in adult patients with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease; this is based on histological, virological, biochemical, and serological responses in adult patients with HBeAg+ and HBeAg- chronic hepatitis B with compensated liver function, and in adult patients with clinical evidence of lamivudine-resistant hepatitis B virus with either compensated or decompensated liver function.

Adapalene supplier & exporter

Product Description

Trader & Wholesaler of Adapalene

Mechanism of Action:

Adapalene is used for the treatment/maintenance of mild-to-severe acne (acne vulgaris). Acne is a multifactorial condition, and evidence exists to support multiple mechanisms of action for adapalene. Adapalene binds to retinoic acid receptor (RAR)-beta and RAR-gamma; this complex subsequently binds to one of three retinoid X receptors (RXRs), which as a complex is capable of binding DNA to modulate transcriptional activity

Drug Indications:

Adapalene is indicated for the topical treatment of acne vulgaris in patients aged 12 and over. Build, train, & validate predictive machine-learning models with structured datasets. Avoid life-threatening adverse drug events & improve clinical decision support.

Acyclovir / Aciclovir supplier & exporter

Product Description

Trader & Wholesaler of Acyclovir

Mechanism of Action:

Acyclovir is becomes acyclovir monophosphate due to the action of viral thymidine kinase.5 Acyclovir monophosphate is converted to the diphosphate form by guanylate kinase.1 Acyclovir diphosphate is converted to acyclovir triphosphate by nucleoside diphosphate kinase, pyruvate kinase, creatine kinase, phosphoglycerate kinase, succinyl-CoA synthetase, phosphoenolpyruvate carboxykinase and adenylosuccinate synthetase.

Drug Indications:

An acyclovir topical cream is indicated to treat recurrent herpes labialis in immunocompetent patients 12 years and older.10 Acyclovir oral tablets, capsules, and suspensions are indicated to treat herpes zoster, genital herpes, and chickenpox.11 An acyclovir topical ointment is indicated to treat initial genital herpes and limited non-life-threatening mucocutaneous herpes simplex in immunocompromised patients.12 An acyclovir cream with hydrocortisone is indicated to treat recurrent herpes labialis, and shortening lesion healing time in patients 6 years and older.13 An acyclovir buccal tablet is indicated for the treatment of recurrent herpes labialis.14 An acyclovir ophthalmic ointment is indicated to treat acute herpetic keratitis.

Acotiamide supplier & exporter

Product Description

Trader & Wholesaler of Acotiamide

Mechanism of Action:

Acotiamide exerts its gastroprokinetic activity via presynaptic M1 and M2 muscarinic receptor inhibition, resulting in enhanced acetylcholine (Ach) release, and via inhibition of AchE activity in the stomach

Drug Indications:

Acotiamide is used in the treatment of functional dyspepsia. It helps to relieve the symptoms like bloating after a meal, pain/discomfort in the upper abdomen and early satiety

Acitretin supplier & exporter

Product Description

Trader & Wholesaler of Acitretin

Mechanism of Action:

Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

Drug Indications:

Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription.

Acetylcysteine supplier & exporter

Product Description

Trader & Wholesaler of Acetylcysteine

Mechanism of Action:

Acetylcysteine’s sulfhydryl groups may hydrolize disulfide bonds within mucin, breaking down the oligomers, and making the mucin less viscous.11,16 Acetylcysteine has also been shown to reduce mucin secretion in rat models.11 It is an antioxidant in its own right but is also deacetylated to cysteine, which participates in the synthesis of the antioxidant glutathione.11 The antioxidant activity may also alter intracellular redox reactions, decreasing phosphorylation of EGFR and MAPK, which decrease transcription of the gene MUC5AC which produces mucin.

Drug Indications:

acetaminophen is used for the treatment of mild to moderate pain and reduction of fever.23 It is available over the counter in various forms, the most common being oral forms.Acetaminophen injection is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever

Acetazolamide supplier & exporter

Product Description

Trader & Wholesaler of Acetazolamide

Mechanism of Action:

Acetazolamide is a carbonic anhydrase inhibitor. The anticonvulsant activity of Acetazolamide may depend on a direct inhibition of carbonic anhydrase in the CNS, which decreases carbon dioxide tension in the pulmonary alveoli, thus increasing arterial oxygen tension. The diuretic effect depends on the inhibition of carbonic anhydrase, causing a reduction in the availability of hydrogen ions for active transport in the renal tubule lumen. This leads to alkaline urine and an increase in the excretion of bicarbonate, sodium, potassium, and water.

Drug Indications:

Acetazolamide is a diuretic and carbonic anhydrase inhibitor medication that is used to treat several illnesses. FDA-approved indications include glaucoma, idiopathic intracranial hypertension, congestive heart failure, altitude sickness, periodic paralysis, and epilepsy.