Abaloparatide supplier & exporter
|Route of Administration||Injection, Tablet|
Trader & Wholesaler of Abaloparatide
Mechanism of Action:
abaloparatide acts as an agonist on PTH type 1 receptor (PTH1R) and activates both G protein–mediated cAMP signaling and β-arrestin-mediated ERK-1/2 signaling pathways with similar potency. Abaloparatide binds to RG conformation of PTH1R with greater selectivity that results in more transient cell signalling responses.
Investigated for use/treatment in postmenopausal osteoporosis to reduce vertebral and/or non-vertebral fractures.