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Abacavir Sulfate

Abacavir Sulfate supplier & exporter

Product Description

API name Abacavir Sulfate
CAS Number 188062-50-2
Therapeutic Category Antiretroviral, Anti HIV
Route of Administration Solution , Tablet
Regulatory Documents DMF, ASMF, USDMF, WC, Tech Pack

Trader & Wholesaler of Abacavir Sulfate

Mechanism of Action:

Abacavir is a carbocyclic synthetic nucleoside analogue and an antiviral agent.Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.Viral DNA growth is terminated because the incorporated nucleotide lacks a 3′-OH group, which is needed to form the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation.

Drug Indications:

Abacavir is indicated in combination with other anti-retroviral agents for the treatment of HIV-1 infection.Abacavir should always be used in combination with other antiretroviral agents. Abacavir should not be added as a single agent when antiretroviral regimens are changed due to loss of virologic respons

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